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1. Q&A: Organon chief communications officer Wendy Lund talks about the Merck spinoff, women’s health and why it matters
2. MarketingRx Matchup: How AbbVie and Biohaven ads rank in head-to-head migraine challenge
3. Thankful for nurses: J&J's new campaign aims to reset pandemic clock back to gratitude
4. Klick Health hands out $100 bills in annual holiday greeting that’s turned into default recruiting tool
5. Digital clutter threatens pharma-to-physician relationships in shift to next era of communications
6. GlaxoSmithKline's friendly ‘shark tank’ crowdsources ideas for multiple myeloma, kicks off bigger push
7. Common, Jamie Foxx among celebs standing up for clinical trials in star-studded cancer group's pandemic push
8. MarketingRx roundup: Pfizer re-ups pneumonia ads as Merck threat looms; Real Chemistry founder CEO Jim Weiss steps back
9. FDA tacks on new warning to AbbVie's Rinvoq label as safety frets crimp JAK class
Beth Snyder Bulik
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It’s all about women today at Endpoints. As we announce the amazing Endpoints’ Women in Biopharma R&D honorees today, MarketingRx checks in with woman’s health marketing maven Wendy Lund, a healthcare agency veteran now at Organon and championing women once again. Also in this week’s issue, check out the new monthly DTC ad battle debut, pitting two competing campaigns against each other to find out what people really think. Thanks for reading and don’t forget to subscribe to get MarketingRx direct to your inbox

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Beth Snyder Bulik
Senior Editor, Endpoints News
@BethSBulik
Wendy Lund, Organon chief communications officer
1
by Beth Snyder Bulik

One of Wendy Lund’s ear­li­est jobs was head of mar­ket­ing at Planned Par­ent­hood. As the youngest per­son on its man­age­ment team, she in­tro­duced them to emerg­ing new tech­nolo­gies, and in re­turn, she learned the im­por­tance of fight­ing for what you be­lieve in.

Now as chief com­mu­ni­ca­tions of­fi­cer at Organon, the women’s health com­pa­ny re­cent­ly spun off by Mer­ck, Lund is keep­ing that point top of mind. That’s in part be­cause women’s health hasn’t been a spot­light ther­a­py area for Big Phar­ma in years. Sev­er­al com­pa­nies have spun off, sold or at least con­sid­ered sell­ing women’s health as­sets to fo­cus on "core" prod­ucts.

Ab­b­Vie is re­port­ed­ly re­view­ing whether it should sell their $5 bil­lion women’s port­fo­lio as part of its gains in its ac­qui­si­tion of Al­ler­gan, which had it­self looked to sell off the same as­sets in 2018 be­fore get­ting bought in 2019. Te­va sold off its women’s health port­fo­lio in 2018, and Pfiz­er re­port­ed­ly con­sid­ered the same in 2019.

Lund, who most re­cent­ly head­ed GCI Health com­mu­ni­ca­tions and PR agency as CEO for 11 years, says that lack of in­ter­est by oth­ers – in­clud­ing biotechs – ap­pealed to her. She saw Organon as a “well-es­tab­lished start­up” tak­ing on women’s health is­sues  that un­for­tu­nate­ly re­main al­most iden­ti­cal to the ones she worked on at Planned Par­ent­hood more than 20 years ago.

Re­cent stats show about 45% of preg­nan­cies in the US are un­in­tend­ed, that’s about the same rate it was 20 years ago.

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2
by Beth Snyder Bulik

Are you ready to rum­ble? DTC brands that is. Mar­ket­ingRx is launch­ing a new month­ly fea­ture to­day called Mar­ket­ingRx Matchup. We’re pit­ting two phar­ma brands’ DTC ad­ver­tis­ing in the same ther­a­peu­tic cat­e­go­ry against each oth­er to find out what con­sumers and pa­tients re­al­ly think.

Mar­ket re­search com­pa­ny Leg­er is han­dling the polling and analy­sis each month, and I'll be writ­ing up the re­sults — along with my own take — in­side MRx on the first Tues­day of the month.

So first up is a lit­er­al head-to-head cam­paign matchup with mi­graine drugs Ubrelvy from Ab­b­Vie and Nurtec ODT from Bio­haven.

Leg­er test­ed three TV ads that all fea­ture mi­graine-suf­fer­ing spokes­peo­ple — a Ubrelvy spot with ten­nis star Ser­e­na Williams, a Nurtec com­mer­cial with ac­tor and talk show host Whoopi Gold­berg and a sec­ond Nurtec ad that fol­lows av­er­age re­al pa­tient named El­lie. The re­searchers showed the ads to 1,001 peo­ple in the US and asked a se­ries of ques­tions, break­ing out spe­cif­ic re­spons­es of the tar­get au­di­ences of peo­ple who have mi­graines.

Be­fore Leg­er pre­viewed the spe­cif­ic TV com­mer­cials, they checked gen­er­al aware­ness, ask­ing if the per­son could re­call see­ing the Ubrelvy or Nurtec ads in the pho­to snap­shot.

Among all peo­ple, 8% re­mem­bered see­ing the Ubrelvy ad and 7% re­mem­ber see­ing the Nurtec ad. How­ev­er, among peo­ple with mi­graine, 11% said they saw the Ubrelvy ad while 18% re­mem­bered the Nurtec ad.

Next Leg­er re­searchers showed the com­mer­cial and asked a se­ries of spe­cif­ic ques­tions to de­ter­mine each one's suc­cess. Did peo­ple un­der­stand the mes­sages that Ab­b­Vie and Bio­haven tried to get across? Do they think the spokes­peo­ple are cred­i­ble?

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Nurses star in J&J's campaign centered on the importance of nurses who are increasingly stressed, burnt out and quitting the profession (via Johnson & Johnson)
3
by Beth Snyder Bulik

In the ear­ly days of the pan­dem­ic, peo­ple cheered for nurs­es – de­liv­er­ing food, writ­ing thank you notes and ring­ing bells night­ly to show their ap­pre­ci­a­tion. But some­thing shift­ed this sum­mer, and now John­son & John­son wants to re­mind peo­ple of the grat­i­tude that nurs­es still de­serve.

Call it pol­i­tics or pan­dem­ic weari­ness or the re­sult of al­most two years of a dead­ly pan­dem­ic, but nurs­es to­day face threats and mis­treat­ment from pa­tients and their an­gry fam­i­ly mem­bers. And nurs­es are leav­ing the pro­fes­sion in record num­bers.

J&J’s new ad cam­paign “Nurs­es Rise to the Chal­lenge Every Day” launch­es on­line and in lo­cal news­pa­pers on Sun­day, aim­ing to shine a pos­i­tive spot­light on the pro­fes­sion. It al­so in­cludes J&J dou­bling down on its ed­u­ca­tion, fel­low­ships, schol­ar­ships and pro­grams to sup­port nurs­es.

In the cam­paign video ad, close-up shots re­veal tired nurs­es in scrubs and as they weari­ly re­move masks, a scroll reads: “You give 100% of your­self, then some­how find 50% more.”

At the heart of the cam­paign are the many roles that nurs­es take on: sci­en­tist, pi­o­neer, heal­er and rock star in the video ad, while the print ad lists dozens more in­clud­ing teacher, ther­a­pist, cheer­leader, en­tre­pre­neur, in­flu­encer, dot-con­nec­tor and mind read­er. So­cial me­dia posts have a sim­i­lar theme with “Nurs­es are” in at­ten­tion-get­ting red let­ters, while the roles scroll and change in the gif an­i­ma­tion.

“When you fast for­ward to where we are now and look around on­line, pret­ty much all you see is stress, burnout and turnover – at up­wards of 20% per year,” said Lyn­da Ben­ton, se­nior di­rec­tor of glob­al com­mu­ni­ty im­pact strate­gic ini­tia­tives for J&J Nurs­ing.

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Klick Health agency employees appear in its annual holiday greeting video with this year's theme to #SpreadJoy (via Klick Health)
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by Beth Snyder Bulik

What would you do with $100 and the sim­ple in­struc­tion to “spread joy?" That’s what phar­ma and health­care agency Klick Health asked its em­ploy­ees as part of its an­nu­al hol­i­day greet­ing for clients, friends and fu­ture re­cruits.

More than 600 Klick­sters, as the agency folks call them­selves, took up the chal­lenge. For each per­son who signed up, Klick sent a box with a roy­al blue agency brand­ed scarf, cards and a $100 bill. Each per­son filmed them­selves open­ing the box, start­ing out on their “joy” mis­sions and their re­cip­i­ents’ re­ac­tions.

The smart­phone videos were then com­piled in­to a three-minute “#Spread­Joy” hol­i­day video, a process that chief cre­ative of­fi­cer Rich Levy said took about three weeks. While the an­nu­al greet­ing is a pop­u­lar tra­di­tion in­side the com­pa­ny, it al­so serves as a de­fault re­cruit­ing tool with mil­lions of views and al­most every in­ter­vie­wee men­tion­ing they’d seen one of the videos. The 2020 an­i­mat­ed video clocked 4.8 mil­lion views while 5.9 mil­lion watched the last pre­vi­ous live-shot video in 2019.

“When you start get­ting that num­ber of views, every­one sees it and every­one re­mem­bers it. I think peo­ple like them be­cause they show what the com­pa­ny stands for, and peo­ple want to work for com­pa­nies that match their per­son­al val­ues,” Levy said.

In the video, some Klick em­ploy­ees hand big tips to wait­ers or baris­tas, while oth­ers gift the mon­ey to bus dri­vers, cross­ing guards and kind neigh­bors.

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5
by Beth Snyder Bulik

Phar­ma com­pa­nies have more dig­i­tal doors to doc­tors than ever be­cause of the Covid-19 pan­dem­ic, but health­care providers think many can do bet­ter.

While 86% of HCPs rec­og­nize that phar­ma com­pa­nies are more con­sid­er­ate of their needs now, al­most two-thirds (65%) al­so say at least one phar­ma has “spammed” them with dig­i­tal con­tent in the past year. And 64% agree that the vol­ume of dig­i­tal con­tent from phar­ma com­pa­nies is too much, ac­cord­ing to the Ac­cen­ture study set for re­lease Mon­day.

“There’s great op­por­tu­ni­ty here, but al­so great cau­tion to be had,” Suzy Jack­son, man­ag­ing di­rec­tor in Ac­cen­ture’s life sci­ence prac­tice, said. “The an­swer is not quan­ti­ty, but qual­i­ty, and mak­ing sure you’re cut­ting through the noise. And if you do so, we’re show­ing that you get re­ward­ed for that.”

That re­ward? More time and at­ten­tion from doc­tors. Time, in fact, is some­thing most HCPs have more of to­day. About three-fourths re­port­ed drops in pa­tient num­bers over the past year, con­sis­tent across spe­cial­ties, in­clud­ing on­col­o­gy (76%), im­munol­o­gy (78%), car­di­ol­o­gy (72%) and gen­er­al prac­tice (73%).

The good news for phar­ma is that more free time – and bet­ter com­mu­ni­ca­tions – trans­lates to more ac­cess with 88% twice as like­ly to meet with a phar­ma rep if it were sim­i­lar to their best in­ter­ac­tions. When ques­tioned fur­ther, they agreed they would be more open to meet­ing oth­ers in the com­pa­ny, open emails and lis­ten to mes­sages from that com­pa­ny ver­sus oth­ers.

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6
by Beth Snyder Bulik

Glax­o­SmithK­line is invit­ing every­one to its friend­ly shark tank. Its “Think Tank” chal­lenge launch­ing to­day aims to gath­er the best pitch­es for ideas in mul­ti­ple myelo­ma with a fi­nal pitch-off “Shark Tank” TV show-style fin­ish next year.

The in­no­va­tion con­test kicks off GSK’s big­ger “Tar­get the Fu­ture” un­brand­ed cam­paign to ad­vance in­no­va­tion and aware­ness in mul­ti­ple myelo­ma.

“We have a good sense of where the un­met need lies and what tools may be wel­comed by this com­mu­ni­ty, and we’ll con­tin­ue to do that as part of this pro­gram, but the 'Think Tank’ kick­off is to bring new ideas to the ta­ble — things that come from a more grass­roots per­spec­tive than a large phar­ma per­spec­tive,” Chris­tine Roth, se­nior VP and glob­al head of on­col­o­gy at GSK, said.

En­tre­pre­neurs, pa­tients, physi­cians, care­givers and ad­vo­cates can sub­mit ideas on­line through Feb. 11. Three fi­nal­ists will be cho­sen to do a live pitch, de­pen­dent on pub­lic health con­di­tions, to on­col­o­gy ex­perts from both in­side and out­side GSK for a top prize of $100,000 and GSK ad­vi­sors and guid­ance to bring the idea to life. The win­ning idea will be judged on im­pact, nov­el­ty, and fea­si­bil­i­ty of ex­e­cu­tion.

The mul­ti-year cam­paign, and now an­nu­al con­test, is nec­es­sary in mul­ti­ple myelo­ma be­cause both treat­ment and care so­lu­tions are still in de­mand. That’s in part be­cause while the can­cer is man­age­able with drug op­tions, it is not cur­able and meds tend to stop be­ing ef­fec­tive af­ter time.

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7
by Beth Snyder Bulik

Health­care screen­ings and clin­i­cal tri­al en­roll­ment were bat­tered by the pan­dem­ic. But the well-known celebri­ty-backed Stand Up To Can­cer non-prof­it, along with phar­ma and ad­vo­ca­cy part­ners, has been work­ing to re­verse that and make up lost ground, by step­ping up aware­ness cam­paigns.

Twelve cam­paigns launched in 2020 and an­oth­er five in 2021 am­pli­fy the need for can­cer screen­ing and care, es­pe­cial­ly for un­der­served com­mu­ni­ties. While phar­ma com­pa­nies have long been donors to the can­cer re­search group, Covid brought new sup­port — and in­creased aware­ness ef­forts.

Rap­per and ac­tor Com­mon most re­cent­ly starred in a Stand Up To Can­cer (SU2C) TV cam­paign to raise lung can­cer treat­ment and clin­i­cal tri­al aware­ness. The TV ad, along with print, dig­i­tal, ra­dio and out-of-home, was backed by $5 mil­lion from Bris­tol Mey­ers Squibb to get the mes­sage out to Black men and women and peo­ple liv­ing in rur­al com­mu­ni­ties.

Com­mon's pub­lic ser­vice an­nounce­ment fol­lowed an­oth­er celebri­ty-led ef­fort from ac­tor Jamie Foxx for can­cer screen­ing fund­ed by Ex­act Sci­ences. In his PSA, Foxx press­es peo­ple to “take con­trol and get screened for col­orec­tal can­cer” in TV, print, ra­dio, dig­i­tal and out-of-home cam­paigns.

Am­gen is an­oth­er phar­ma part­ner back­ing print, dig­i­tal and out-of-home ads for SU2C's Health Eq­ui­ty Ini­tia­tive to in­crease clin­i­cal tri­al aware­ness and par­tic­i­pa­tion. The ef­fort in­cludes a se­ries of ads aim­ing to in­crease di­ver­si­ty in clin­i­cal tri­als with co­me­di­an and ac­tor Cedric the en­ter­tain­er and ac­tors Sonequa Mar­tin-Green and Jaime Camil.

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8
by Beth Snyder Bulik

Every au­tumn, leaves fall from the trees and peo­ple start hol­i­day shop­ping – and for the last few years Pfiz­er de­buts a new “Know Pneu­mo­nia” aware­ness TV ad. This year the com­mer­cial, launched a week ago, fea­tures dif­fer­ent peo­ple who talk about why they got vac­ci­nat­ed against pneu­mo­coc­cal pneu­mo­nia. Ac­tors por­tray a young fe­male fire­fight­er with asth­ma, a me­chan­ic with heart dis­ease and an old­er woman with her grand­child. A Pfiz­er spokesper­son de­clined com­ment on the lat­est it­er­a­tion of the long-run­ning cam­paign.

While the ef­fort is un­brand­ed, it be­gan dur­ing Pfiz­er’s long-run­ning Pre­vnar 13 pneu­mo­coc­cal vac­cine run. Pfiz­er’s best-sell­ing drug – notch­ing sales of just un­der $6 bil­lion in 2020 – has al­so been the world’s top-sell­ing vac­cine for more than a decade, on­ly end­ing this year be­cause of Covid-19 vac­cines.

The next it­er­a­tion of the vac­cine, a 20-va­lent pneu­mo­coc­cal vac­cine du­ly named Pre­vnar 20, re­ceived FDA ap­proval in June. Pfiz­er re­cent­ly post­ed pos­i­tive study re­sults from test­ing a dual Pre­vnar 20 and sea­son­al in­fluen­za vac­ci­na­tion sched­ule.

Pfiz­er's top spot in pneu­mo­coc­cal vac­cines, though, could be in je­or­pardy for the first time this sea­son with com­pe­ti­tion from Mer­ck­'s 15-va­lent Vaxneu­vance ap­proved in Ju­ly. Al­though an­a­lysts ex­pect Pfiz­er to keep a ma­jor­i­ty of the mar­ket, Mer­ck may cap­ture a siz­able mi­nor­i­ty.

Pos­si­bly spurring the mar­ket share war even more this sea­son is CDC guid­ance to add chron­ic con­di­tion rec­om­men­da­tions to the tra­di­tion­al 65-plus tar­get. For the first time, the Ad­vi­so­ry Com­mit­tee on Im­mu­niza­tion Prac­tices (ACIP) added adults 19-64 with un­der­ly­ing chron­ic con­di­tions in­clud­ing di­a­betes, as well as heart, lung and kid­ney dis­ease.

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9
by John Carroll

The safe­ty prob­lems that con­tin­ue to plague the JAK class as new da­ta high­light some se­vere side ef­fects are cast­ing a large shad­ow over Ab­b­Vie’s Rin­voq.

As a re­sult of a re­cent read­out high­light­ing ma­jor ad­verse car­diac events (MACE), ma­lig­nan­cy, mor­tal­i­ty and throm­bo­sis with Xel­janz a cou­ple of months ago, Ab­b­Vie put out a no­tice late Fri­day af­ter­noon that the class risks are be­ing added to its la­bel for their ri­val drug, which will now be rel­e­gat­ed to sec­ond-line use.

Says Ab­b­Vie:

The in­di­ca­tion has al­so been up­dat­ed to the fol­low­ing: RIN­VOQ is in­di­cat­ed for the treat­ment of adults with mod­er­ate­ly to se­vere­ly ac­tive rheuma­toid arthri­tis who have had an in­ad­e­quate re­sponse or in­tol­er­ance to one or more TNF block­ers.

That's not go­ing to help their mar­ket­ing ef­forts, notes SVB Leerink's Ge­of­frey Porges, but it's not as bad as the black box alert the agency re­quired for Pfiz­er's block­buster Xel­janz. Porges not­ed:

It ap­pears AB­BV suc­cess­ful­ly ne­go­ti­at­ed milder lan­guage on mor­tal­i­ty and MACE than the boxed warn­ing for Xel­janz, as well some more fa­vor­able lan­guage on ma­lig­nan­cies. Fur­ther, there were no re­stric­tions on du­ra­tion of use, which was an un­like­ly but bear­ish sce­nario for the drug. How­ev­er, these are all mi­nor wins in light of the ma­jor scruti­ny on the JAK in­hibitor class over the last year, and with the up­dat­ed la­bels, the FDA has made it clear that they be­lieve MACE, ma­lig­nan­cy, and throm­bo­sis to be class ef­fects for JAKs.

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